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Peter Attia 18 Feb 23 Lean mass loss on GLP-1 receptor agonists: a downside of the miracle drugs Clinical trials have generated impressive data on the effects of GLP-1 agonists on body weight and BMI, but how do these drugs perform in terms of body composition

It slows down gastric emptyingkeeping food in your stomach longerand signals the satiety centers of the brain to stop cravings and intrusive thoughts about food

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Phase 2 orforglipron data demonstrated 14.7% body weight reduction at 45mg without food or water requirements, and the addressable patient expansion is estimated to grow the anti-obesity medication market by 180 million new prescription patients between 2027 and 2032

Whats Coming Next for GLP-1 and Metabolic Disease Treatment Moving from academia to industry led to advancing groundbreaking diabetes and obesity therapies

She is suing Eli Lilly because she believes the company downplayed the Trulicity side effects and did not tell consumers these complications could occur