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However, these Tregs exhibited increased expression of IL-17a and Rort (Figure 3, N and O), markers associated with Th17 cells rather than the immunosuppressive Tregs This dysfunctional Treg phenotype aligns with the chronic, low-grade inflammatory state observed in the eWAT of Bbs5 / mice

Age-dependent ferritin elevations and hfe C282y mutation as risk factors for symptomatic knee osteoarthritis in males: A longitudinal cohort study

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Additionally, 5 of the 6 patients (83%) for whom this information was available died of their disease

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