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Many recommendations are based on analogies to similar diseases (chronic inflammation, lymphoedema, obesity, arthritis) and pathophysiological considerations

Interestingly, necroptosis and autophagy pathways have emerged recently and have been shown to have a crucial role in CP-induced AKI (Rovetta et al., 2012

M., & McClements, D

In adults, it supports muscle protein synthesis, lipolysis (fat breakdown), cellular repair, and metabolic homeostasis