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To determine whether the improved PK properties of the QMP-engineered fusions would translate into enhanced efficacy, we repeated the GTT in human FcRn Tg32 mice

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These improvements may also impact the broader medical insurance sector, potentially leading to both reduced premiums and reduced claims burdens

However, the translation to clinical efficacy in human osteoarthritis remains ambiguous, as weight loss appears to play a substantial role in pain alleviation [21, 22]

The larger benefit with the additional agonism of GIPr seems to be its effect on weight loss