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Ipamorelina activa GHSR-1a (Gq/11 calcio + PKC) y arcuato hipotalmico (inhibe somatostatina)

** Azorubine: may have a detrimental effect on activity and attention in children

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Tan Q, Akindehin SE, Orsso CE, Waldner RC, DiMarchi RD, Muller TD, et al

GLP-1 agonists, such as ROSE-010, relieve pain in IBS patients by altering gut motility (43), lowering inflammation (44), modulating neurotransmitters (45), reducing visceral hypersensitivity (46), and interacting with the gut microbiota (47)

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