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Persistent oxidative stress after ionizing radiation is involved in inherited radiosensitivity

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Pycnogenol has been shown to be a powerful antioxidant in laboratory tests and clinical studies.[] Pycnogenol improves antioxidant capacity, endothelial function, vascular integrity and has significant anti-inflammatory potential in humans.[] The radical scavenging properties described of Pycnogenol were assumed to have a potential radioprotective effect

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If a patient has a very strong reaction they may need to discontinue the infusion

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Proteins 81 , 16211633 (2013)

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The protein expression levels of tight junction associated protein-1 (ZO-1), Occludin, inflammatory factors interleukin (IL)-6, IL-1 and tumor necrosis factor (TNF)-, SIRT1, STAT3, p-STAT3, and retinoic acid receptor-related orphan receptor gamma t (RORt) were detected by Western blot

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