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The small sample size is also listed as another potential limitation of the study

Our discussion is based on interpreting the existing body of preclinical evidence for research design purposes

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These include vomiting, nausea, and diarrhea

In addition, as the Variant Call Format (VCF) file of every patient is already generated, if future scientific literature highlights new variants, or genes of clinical relevance, there is no need to obtain a new sample or repeat an expensive sequencing procedure