[2] [19] There is also a risk of gallbladder disease (cholelithiasis, cholecystitis), acute kidney injury secondary to dehydration from gastrointestinal effects, and rare but serious risks such as pancreatitis and thyroid C-cell tumours (observed in animal studies)
The role of endogenous GLP-1 signaling in the lung is likely multifactorial and much more complex, particularly in a diseased state, and may depend on the mechanism of pulmonary injury
b , Representative micrograph of the TT-OAD2GLP-1RG s complex
Conclusions and Relevance Results of this study suggest a modest increase in the risk of NAION among individuals with T2D associated with semaglutide use, smaller than that previously reported, and warranting further investigation into the clinical implications of this association
Instead, the therapeutic response must be oriented to an individuals specific configuration of needs
The Food and Drug Administration requires drug companies to run studies investigating whether GLP-1s increase the risk of cardiovascular problems a mandate for all diabetes drugs
