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Interestingly, the patients who received the combined treatment experienced less overall improvement than those taking either form individually, suggesting that massive doses of competing carnitine forms might overwhelm cellular transport mechanisms

Frontiers in Nutrition, 2025, DOI: 10.3389/fnut.2025.1566498,

[2] Phentermine maintains a long-standing record in obesity treatment, receiving FDA approval as a resin complex in 1959 and then as a hydrochloride salt in 1973 for short-term weight management

That distinction changes everything

Both medications are processed in your body by similar systems, including the liver and kidneys