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The -oxidation is normally responsible for only a small component of VPA metabolism (Fig

SIRT2-mediated deacetylation and activation of G6PD stimulates oxidative branch of PPP to supply cytosolic NADPH to counteract oxidative damage or support de novo lipogenesis

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Mostly used cytotoxic molecules inhibit tubulin, are immunomodulators or they damage DNA (164)

In this context, genetic transformation stands out as a promising strategy to improve key agronomic and quality traits, and greater effort should be directed toward generating more stable phenotypes