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[1] [3] It should be avoided in patients with Leber's hereditary optic neuropathy

This creates a common certificate-of-analysis problem

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[73] [74] [75] It is synthesized by some bacteria in the gut microbiota in humans and other animals, but it has long been thought that humans cannot absorb this as it is made in the colon, downstream from the small intestine, where the absorption of most nutrients occurs

In this case I stop, change needles and choose another site