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For weekly medications, the timing has less impact on side effects due to their steady-state pharmacokinetics

Another practical observation is that many people regain weight once the medication is stopped, suggesting the underlying metabolic drivers may not have been fully addressed

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GLP-1 receptor agonists reduce appetite, make digestion happen more gradually and support steady calorie reduction

The study demonstrated a clear benefit for semaglutide, with a 24% lower risk to reach the primary outcome in the semaglutide group versus the placebo group