We found that deletion of IGF1R in Nestin + MSCs affected the differentiation, but not migration of MSCs during bone remodeling
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We defined somatic comorbidity as having type 1 and 2 diabetes (ICD-10: E10, E11, E14), obesity (ICD-10: E66), heart disease (ICD-10: I20-I25), stroke (ICD-10: I61, I63, I64, G45) within 10 years prior to index date
However, the benefits of probiotics can differ based on whether the bacteria are living or dried (lyophilized), and whether they are administered in combination (multi-strain) or alone (single-strain) [20]