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Without water present, the chemical reactions that degrade peptides, primarily hydrolysis, essentially stop

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Moreover, the number of senescent cells also increase with culture time, resulting in a loss of division capabilities, resistance to apoptosis, and the acquisition of a robust proinflammatory secretome known as the senescence-associated secretory phenotype (SASP) (Jeon et al., 2018)

J Cell Mol Med (2011) 15(4):70117.10.1111/j.1582-4934.2010.01237.x 78 TajtiJMajlathZSzokDCsatiAToldiJFulopFet alNovel kynurenic acid analogues in the treatment of migraine and neurodegenerative disorders: preclinical studies and pharmaceutical design