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They work as GLP-1 receptor agonists that mimic the feeling of fullness or satiety

In November 2024, the Biden administration proposed expanding Medicare and Medicaid coverage for anti- obesity drugs, potentially extending coverage to an estimated 3.4 million Americans insured by Medicare and an additional four million by Medicaid

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Eating smaller, more frequent meals rather than large portions reduces gastric distress

Third, the TRIUMPH-4 population (obesity plus knee OA) is slightly different from the STEP-1 and SURMOUNT-1 populations (general obesity), so the definitive head-to-head comparison waits for TRIUMPH-1

Of the participants with both EHR and survey data, 125 self-reported using semaglutide, of whom 97.6% had a corroborating EHR record