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Here are some common ones: Gastrointestinal Issues: Nausea, vomiting, diarrhea, constipation, or abdominal pain are some of the most frequently reported side effects

In fact, a 2025 study published in JAMA cites steep list prices (over $1000 a month) and spotty insurance coverage as top reasons why most people seeking to lose weight quit taking meds like Ozempic or Vaxenda within a year

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doi: 10.1155/2015/537689

Does the maintenance dose ever stop working

MASH represents a significant health burden, with one in three people with overweight or obesity worldwide affected