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doi: 10.1016/j.hsr.2025.100219 70 SiddiquiAJAdnanMSaxenaJAlamMJAbdelgadirABadraouiRet al

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After incubation, mitochondria were pelleted (1 min at 16,000 g ) and pellets were resuspended in 200 L of 50 mM HEPES buffer (pH 7.4) supplemented with 10 mM IAM-TPP, disrupted using mechanical micro-homogeniser and sonicated for 5 min

Moreover, DSIP has demonstrated the capacity to attenuate sleep initiation latency and minimize nocturnal arousal in preclinical studies on laboratory models

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Dosage: 200-500 mcg, 1-2 times daily via subcutaneous injection or daily oral capsules