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PLAIN ENGLISH Each KLOW compound targets a real biological process

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14,40 However, the potency data for stimulation of cAMP production collectively suggest that signal transduction via G s is facilitated if the receptor-bound ligand retains flexibility and can access a non-helical conformation near the N-terminus

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While clinical trials did monitor for psychiatric adverse events, they did not specifically focus on irritability or anger as primary endpoints

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Journal of Agricultural and Food Chemistry, 67(18), 4876-4886

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