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MOTS-c has attracted considerable scientific interest because of its role in metabolism, and early human studies have begun, but there is currently insufficient evidence to support its use for obesity or osteoporosis, Dr

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Rights and permissions About this article Cite this article LeRoith, D., Yakar, S

& Gelfand, M

For instance, it healed transected muscles and counteracted NSAID toxicity without adverse effects.[24][25] Clinical Trials : A Phase I trial (NCT02637284) confirmed safety and pharmacokinetics in healthy volunteers, with no serious adverse events.[26] Phase II trials for ulcerative colitis showed encouraging results, with BPC-157 promoting remission.[27] A recent trial in inflammatory bowel disease patients reported tolerability and potential benefits.[28] The table below highlights select key studies: While robust, the reliance on animal models underscores the need for more large-scale human trials