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Hepatic Steatosis and MASLD The glucagon receptor arm drives hepatic lipid oxidation and reduces liver fat independent of caloric restriction alone [3]

Pennisi M, et al

doi: 10.1507/endocrj.ej15-0749 29 PerriniSLaviolaLCarreiraMCCignarelliANatalicchioAGiorginoF

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The proteins identified in Table 4 meet specific criteria for -cell protection elicited by GLP-1RAs: they are activated and/or induced by GLP-1RAs in -cells, and their inhibition and/or suppression diminish the protective effects of GLP-1RAs against cell death induced by pro-apoptotic stressors