Highlights This paper systematically reviews the relationship between nutrition, microbiota, and depression
Microneedling creates transient microchannels in the scalp that bypass the stratum corneum and allow topical actives to reach the follicular unit at depths that surface application cannot achieve
With regular use, your skin looks brighter, hydrated, and visibly refreshed
New onset metabolic disorders also include type 2 diabetes mellitus (T2DM), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and dysautonomia, especially the postural orthostatic tachycardia syndrome (POTS) 8,9,10,11
The IGF-1/p53-mediated cellular senescence (see above) might also be induced by the STAT3/SOCS pathway
In a study using human skin tissue models (including ex vivo skin samples), Pep 14 reduced markers of cellular aging, promoted DNA repair, decreased inflammation, increased cellular renewal and collagen expression, and led to a reduction in the biological age of skin tissue by an average of 2.6 years after just five days of topical treatment
