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In adipocytes, GPR81 acts synergistically with insulin to lower intracellular cyclic adenosine monophosphate (cAMP) levels, thereby suppressing postprandial lipolysis (52)

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Effect of pembrolizumab plus neoadjuvant chemotherapy on pathologic complete response in women with early-stage breast cancer: an analysis of the ongoing phase 2 adaptively randomized I-SPY2 trial