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UV irradiation induces DNA damage that can lead to nucleotide alterations and beneficial mutations (Lawrence et al., 1982)

Considering their low MW and non-covalent nature of inhibition of TGR, these compounds were deemed appropriate for fragment-based design

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Even my eyes were bloodshot

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Within hours after ischaemia onset, associated cytokine- and chemoattractant-mediated endothelial dysfunction, apoptosis, autophagy, platelet aggregation and micromebolization and neutrophil accumulation as well as macrophage and T-cell-mediated cell-damage occur [90, 91]