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Its also used off-label for anti-aging purposes, athletic performance enhancement, and body composition improvement

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When NNMT is turned down, lab models show adipocytes shrink , cellular energy expenditure cues rise, and inflammatory noise softens

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In this trial, only vitamin E met the prespecified significance level of the primary outcome (i.e., improvement in histological findings, which included an improvement in hepatocellular ballooning), although both active treatment groups had a significant reduction in steatosis, lobular inflammation, and NAS (NAFLD activity score)

Reduce pigmentation 2