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In conclusion, we provide clear evidence for the reinforcement of lymphocyte adhesion by TNF inside-out signaling, thereby highlighting a novel function of TNF in the regulation of immunological adhesion of T lymphocytes and pointing to yet another, so far undiscovered, role of TNF in T cell-mediated adaptive immunity

10.1016/j.ophtha.2016.09.023 40 DewettD.Lam-KamathK.PoupaultC.KhuranaH.RisterJ

Dermatol 21, 173225

Such interactions can significantly alter therapeutic outcomes and adverse effect profiles

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