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Description

The main difference between eryptosis and senescence of RBCs is the time constant of clearance, and it was shown that ionomycin-treated eryptotic mouse cells are cleared within minutes, whereas the clearance process of normal, healthy mouse erythrocytes takes several days [417]

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This indicates substantial structural divergence beyond the conserved core

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Broadly, the goal of these efforts is to enhance the resilience of photoreceptors against cellular stress associated with being separated from the RPE

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