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According to product SmPCs, there is no contraindication to using macrogol-based osmotic laxatives alongside Wegovy

Furthermore, the increased abundance of a sulphite reductase (AFUA_2G15590) observed could indicate an increased need for sulphur in order to biosynthesise EGT

2 Real-world results tell a more nuanced story

Clinical patterns: Findings such as early greying may reflect oxidative stress but are considered observational rather than diagnostic

Dosing: Determined by your healthcare provider to ensure safety and effectiveness

Many jurisdictions have specific regulations surrounding the sale and use of these substances