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The second peak, mediated at least in part by NOX1, NOX3 and mitochondrial enzymes, results in prolonged signaling through PI3K, NF-B, and AKT
Diabetologia 60 (9), 17121721
In aging brains, astrocytes undergo structural and functional alterations
Cells were seeded in advanced DMEM/F-12 (Thermofisher) supplemented with R-Spondin (10% v/v) and Noggin (10% v/v) conditioned media, B-27 supplement (Thermofisher) (1X), nicotinamide (10 mM) and FBS (1%)