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Further, its anti-asthma effects were also improved, evidence by improved asthma-associated inflammation, including eosinophil production, OVA-specific IgE, IL-4, IL-5, and IFN- at 10 mg/kg compared to the group that received 20 mg/kg of free isoliquiritigenin [116]

Inhaled glutathione preparations may trigger respiratory symptoms in individuals with asthma, including wheezing or breathing difficulties

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PTEN exerts its anti-tumor effect mainly by acting on the downstream target molecule PIP3 of PI3K through its lipid phosphatase activity, thereby blocking the PI3K/Akt signaling pathway [53]