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Key findings include: Dose-dependent improvements in neurological function scores at doses 2.5 ml/kg in rat models Reduced infarct volumes in middle cerebral artery occlusion (MCAO) models Enhanced functional recovery when combined with rehabilitation protocols Protection against excitotoxicity and oxidative stress in acute phase Studies using embolic stroke models showed that Cerebrolysin at 5 ml/kg significantly reduced lesion volume and improved sensorimotor outcomes when treatment began 4 hours post-stroke[8]

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Cells were washed with PBS and then incubated with 5 M MitoSOX Red Reagent (Invitrogen) for 10 min at 37 o C