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Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD

However, retatrutide may have superior benefits for insulin resistance and glycemic regulation , due to: Enhanced insulin sensitivity from GIP agonism Reduced hepatic glucose output from glucagon signaling modulation Improved beta-cell function Clinical Insight: Retatrutide reduced fasting glucose and A1C levels with similar or better efficacy than tirzepatide in early trials

Curr Hepatol Rep 15:134139

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