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Maintaining cellular health : Enough NAD+ is vital for energy metabolism and cellular health

3 Molecular functions of ChaC1 ChaC1 and its homologues function as -glutamyl cyclotransferases (GCTs) that specifically degrade glutathione

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The ferroxidase activity of ferritin is associated with H-ferritin

However, when intracellular levels of labile Fe2+ become excessively high, it reacts with hydroxyl radicals via the Fenton reaction, triggering a surge in reactive oxygen species (ROS) production and the accumulation of lipid peroxidation