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The MAPK and Akt inhibitors, UO126 and Akt inhibitor VIII respectively, were used to determine to what extent, if any, activation of their targets is required for Dihexa-mediated protection

5 A diet built around whole foods, protein, fiber, and fewer ultra-processed foods may support a healthier gut environment

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Specific genetic variants in GLP1R, GIPR, FTO, and MC4R genes influence receptor sensitivity, appetite regulation, and baseline metabolic rate, affecting both efficacy and tolerability

Moreover, standardized effect sizes were regressed on their precision, where slope (precision_egger) = 0.4229 (standard error = 0.267), and t = 1.582 and P = 0.175 were not statistically significant