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Its tri-agonist receptor activity supports research into receptor pharmacology, endocrine pathway regulation, lipid metabolism, hepatic signaling, and cross-tissue metabolic communication in controlled laboratory and translational research environments [1][5]

65 In this regard, the incretin hormones, namely GIP and GLP-1, represent key targets for the treatment of T2D and obesity, but are also known to play significant roles in bone metabolism, especially in terms of GIP

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Triple agonists take this strategy further by targeting GLP-1R, GIPR, and the glucagon receptor (GCGR), aiming to regulate multiple complementary metabolic pathways

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