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However, it can also be administered slowly intravenously or subcutaneously (injected into a vein or under the skin)

Kong BS, Min SH, Lee C, Cho YM

The main issue is more practical: tirzepatide slows gastric emptying , which can change the absorption of oral medicines, particularly those where small dose differences matter (and levothyroxine is one of them)

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It works on the gut and brain to help aid hunger regulation

The post says most users experience peak nausea during dose escalation, with symptoms typically resolving within 2-4 weeks after the dose stabilizes