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developed a peptide called FOXO4-DRI, which disrupts the interaction between FOXO4 and p53, leading to p53/p21CIP1-dependent apoptosis in senescent cells

The most commonly reported effects are mild injection site reactions (redness, minor swelling), occasional headaches during the first few days, and rare instances of mild fatigue

These globular proteins have an N-terminal domain that consists of a mixture of alpha-helices and beta strands, while the C-terminal domain is all-helical

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