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During this phase, prolactin acts synergistically with other endocrine factors and local regulatory mechanisms in mammary glands to orchestrate systemic and tissue-specific metabolic adaptations ( de novo lipogenesis and lipid uptake in adipocytes and augmenting the lipid biosynthetic capacity in mammary epithelial cells ( 3 Clinical challenges Clinical studies have consistently reported the association between hyperprolactinemia and obesity

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They are sophisticated signaling molecules known as peptides, designed to interact with very specific receptors in the body

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