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Abstract Introduction: Methotrexate (MTX), a folic acid antagonist and nucleotide synthesis inhibitor, is a cornerstone drug used against acute lymphoblastic leukemia (ALL), but its mechanism of action and resistance continues to be unraveled even after decades of clinical use

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Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest

He D, Cui W, Pang X, Dong J, Qiu Q, Dong H, et al

Oral contraceptive efficacy may be reduced during initiation and dose escalation, based on class data from the tirzepatide SmPC