A landmark analysis using the EPIC cohort (~400,000 European adults, 13-year follow-up) found a J-shaped curve but also found similar J-shaped patterns for conditions where no biological mechanism would explain alcohol protection (e.g., respiratory disease)
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Thakkar et al., 2013
Mid-range products from $2-3 typically balance proven efficacy with business-friendly MOQs
Its main mechanism appears to be its interaction with the nitric oxide (NO) system and its ability to upregulate growth factors like Vascular Endothelial Growth Factor (VEGF)
K., Hellemann, G., Green, M
