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The Nrf2 pathway is thus considered a key modulator of the oxidant/antioxidant balance and it has been shown that (poly)phenolic compounds could induce a response in targeted cells, leading to the activation of several defence enzymes such as glutathione-S-transferase, haem oxygenase 1, quinone oxidoreductase 1 and glutamyl-cysteine ligase (Reference Satta, Mahmoud and Wilkinson84)

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Our experience shows that researchers often begin with a lower concentration, such as 1-2 M, and then gradually increase it to observe dose-dependent effects

More research is needed to determine the long-term clinical benefits and risks of CJC-1295 for the wellness and body-composition uses commonly promoted today