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[63] encompassing 1895 patients with T2DM reported a greater reduction in HbA1c, body weight, FPG, systolic blood pressure, BMI, and low-density lipoprotein cholesterol in a combination therapy group, compared to monotherapy with either GLP-1RA or SGLT-2i

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Compare that to the nausea and GI distress commonly reported with pharmaceutical GLP-1 medications, particularly during dose escalation

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