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Thioredoxins reduce disulfide bonds in oxidized proteins, converting them back to their functional thiol form ( While the GSH, Grx, and Trx systems operate via distinct enzymatic pathways they converge functionally to create a cooperative redox buffering machine
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Further, lipid peroxidation has been found to decrease the membrane's ability to uptake glucose as well as respond to varying levels of immune challenges[7]
