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Interestingly, chronic oral administration of rotenone to rodents in vivo induces many key features of PD, including selectively and progressive nigrostriatal DA neurodegeneration, abnormal behaviours (not seen in the MPTP mouse model) and formation of Lewy bodies (not seen in either the MPTP or 6-OHDA mouse model) 30

10.1016/j.joca.2013.01.014 Osteoarthr

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We aimed to access the efficacy and safety of ALC for the treatment of patients with PNP

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Of note, in vitro analyses demonstrated that targeting Gln metabolism activated the pro-survival ATG5-mediated autophagy, replenishing cell energy and biosynthesis under nutrient-deprivation conditions, and its blockade resulted in more efficient radiosensitization of PCa cells [6,135]