Early signs of mild dehydration include: Thirst and dry mouth Dark yellow or amber-colored urine healthy hydration typically produces pale yellow urine Decreased urination frequency or volume Fatigue and reduced energy levels often attributed to medication but may reflect dehydration Headaches particularly if new or worsening since starting therapy Dry skin and lips More concerning signs of moderate dehydration warrant prompt medical attention: Dizziness or lightheadedness , especially when standing (orthostatic symptoms) Rapid heartbeat or palpitations Confusion or difficulty concentrating Dry mucous membranes (mouth, eyes) Severe constipation unresponsive to usual measures Muscle cramps or weakness Patients with diabetes should be particularly vigilant, as dehydration can affect blood glucose readings and may contribute to hyperglycemic hyperosmolar state (HHS) in type 2 diabetes

Proximal and overall gastric emptying of solids in patients with reduced gastric volume accommodation compared to matched controls
Plan lighter meals for the first few days after increasing your dose
Compounding includes the combining of two or more drugs. Semaglutide, a type of drug called a GLP-1 agonist, is FDA-approved as Ozempic and Rybelsus to treat type 2 diabetes and as Wegovy to treat overweight and obesity
Step 3: Clean your chosen injection site with an alcohol swab
Now, scientists are exploring whether they might be just as transformative in treating a wide range of other conditions, from addiction and liver disease to a common cause of infertility