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doi: 10.1016/j.cell.2016.11.018 12

A new clinical trial found that taking a popular diabetes and weight-loss drug once weekly significantly improves blood sugar and leads to substantial weight loss in adults with Type 1 diabetes who use automated insulin delivery systems

This is approximately up to 3 to 4 days after discontinuing the drug Diphenhydramine as determined by the elimination half-life of Diphenhydramine

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Tirzepatide activates both GLP-1 and GIP receptors, creating a broader appetite and energy regulation signal than semaglutide alone