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While electrophoretic mobility shift assays and mass spectrometry data both suggested a potential role of this mixed disulfide for catalysis 26 , kinetic assays later revealed the irrelevance for the catalytic cycle and thus confirmed that the Grx(SSR) species was an artifact 29

Neuropsychopharmacology , 33 (9), 21872199

Injectable forms are often considered more effective for systemic targets (tendons, joints, muscles) because they bypass digestive breakdown and provide higher bioavailability

For instance, MEK1 inhibitors have been shown to improve cardiac function and reverse myocardial fibrosis and hypertrophy [185]