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Research has shown they are effective for weight loss, but weight gain may occur if a person stops using them

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doi:10.1016/j.cell.2015.05.056 Griffith OW, Meister A (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

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Thats crucial because high levels of homocysteine have been linked to poor sperm quality, low sperm count, reduced motility and higher DNA fragmentation