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According to the MHRA/EMC SmPC, these include: Nausea (very common) Vomiting (very common) Diarrhoea (very common) Abdominal pain (common) Constipation (common) Dyspepsia/indigestion (common) Belching/eructation (common) These effects are typically dose-dependent and most pronounced during treatment initiation or dose escalation

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T., Yan, Y., Sitaraman, S., & Merlin, D

Beyond weight loss, semaglutide improved a broad range of cardiometabolic parameters in ESSENCE [7] , consistent with prior data in T2DM and obesity [10,12]