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3 GLP-1s are multi-system therapies

Mesothelioma cancer cells are glutamine addicted and glutamine restriction reduces YAP1 signaling to attenuate tumor formation

Only Resmetirom (a thyroid hormone receptor beta agonist) has FDA approval for this indication although there are several other drugs in the pipeline

Reduce the dose by 50% and extend the titration schedule

With rising competition among Indian pharmaceutical companies and increasing awareness, GLP-1 therapies are poised to redefine obesity treatment, potentially becoming a key component of long-term weight management strategies in India

It can make high blood pressure harder to control, raise the risk of type 2 diabetes, worsen sleep apnea, increase inflammation, and make the heart work harder than it should