This page is for general educational purposes and is not medical advice
Starting with a single peptide allows you to assess your individual response, identify any side effects, and establish a baseline before adding complexity
Common Side Effects: Injection site reactions (erythema, pruritus, pain) Arthralgia (joint pain) Peripheral edema (fluid retention) Myalgia (muscle pain) Pain in extremities Important Warnings: Contraindicated in active malignancy: GH/IGF-1 promote cell proliferation Contraindicated in pregnancy: Category X Glucose monitoring required: May affect glucose metabolism IGF-1 monitoring recommended: To assess response and safety Rare but Serious: Potential tumor growth stimulation Glucose intolerance/diabetes exacerbation Hypersensitivity reactions Fluid retention complications Regulatory Status United States: FDA approved (2010) for HIV-associated lipodystrophy
To achieve each niclosamide concentration, the 30mM stock solution was made by weighing 100.09mg of AK Sci niclosamide powder (i.e., 98.13mg of niclosamide, allowing for the 2% impurity that is filtered out later) and dissolving in ethanol up to 10mLs total volume
Additional complexity arises from the extrinsic apoptosis pathway, in which Caspase-8 cleaves Bid into tBid, which then cooperates with Bax to permeabilize the mitochondrial membrane [217, 218]
This is the patient whose standard labs are normal and whose doctor suggests burnout